The Rise of the Writers of the Republic of China

In the next half a month, Zhou Hexuan took Guo Taiqi to visit British celebrities around, and at the same time he was carrying out his real estate business.

First of all, Zhou Hexuan bought a villa in the suburbs of London as his and Vivien Leigh's exotic love nest. Immediately afterwards, Zhou Hexuan bought several factories north of Hampton Palace, including the factories, machines and land.

The factory is located in the later London Bushy Park (the second largest royal park in the UK), but it is still an industrial area at this time. There are factories of all kinds, large and small, affected by the global economic crisis, 20% of the factories here are in a state of shutdown, and 30% of the factories are in a state of semi-shutdown.

There are three main reasons why Zhou Hexuan chose to buy land here: first, it is close to the Thames River, and the transportation is convenient; second, the price of industrial land has plummeted and is very cheap; will affect here.

At this moment, good news came from University College London.

Aldrich and his students analyzed the active ingredients of "Pernadox" and decomposed a substance called "sulfanilamide". (Old Wang doesn’t understand medicine, so he confuses sulfonamide with sulfonamide. It’s still easy to find sulfasulfonamide. The contents of the previous chapters have been revised, sorry.)

"Sulfonamide" is "sulfonamide" in the traditional sense, and it is an antibacterial substance produced in the body of living things after taking "Puronidoxil". Moreover, it is also an intermediate of other sulfonamide drugs. If anyone wants to develop more advanced sulfa drugs in the future, they must use "sulfonamide" to make it.

That is to say, as long as Zhou Hexuan applied for the patent of "Sulfonamide", all sulfa drugs would be choked.

Aldridge pointed to the powder in the glass dish and said excitedly: "Zhou, this is the substance that can kill streptococcus. After taking Prontosil, the mice will form a bactericidal substance in their body. We are very lucky , I found it after only five experiments, and I called it Sulfonamide. Sulfonamide can also kill other bacteria, as long as the powder is applied to the wound surface, it can effectively inhibit the growth of bacteria.”

Zhou Hexuan asked: "Can Sulfonamide be produced on a large scale?"

"Should be no problem," Aldrich thought for a while and said, "The structure of sulfamic acid is not complicated, and it can be easily synthesized in the laboratory. As for the method of large-scale production, we need to continue to explore. I believe it will not take long. , a new drug that 'cures all diseases' will be born."

"Then please," Zhou Hexuan said happily, "You prepare the relevant materials, and I will apply for a patent."

Aldrich reminded: "You'd better go to the president of University College London first, and I can introduce you to you. With the help of the school, you can apply for a patent."

Zhou Hexuan was dizzy: "What does this have to do with the University of London?"

"Of course it's related." Aldrich smiled and began to explain.

It turns out that it is very complicated to apply for a drug patent in the UK at this time, and it is necessary to obtain the support of relevant institutions. The most authoritative institution is called the "UK Medical Research Council (MRC)". In addition, the support of universities such as Cambridge, Oxford, and London is also acceptable.

Without the approval of these authorities, the UK patent office will not approve it. Historically, penicillin was unable to obtain a patent in the UK because MRC and Oxford University did not approve it, and finally had to go to the United States for development.

Fortunately, Zhou Hexuan was rich. He directly donated 10,000 pounds to the University of London. With his own fame and the effective bactericidal effect of sulfanilamide, he soon won institutional support from the University of London.

Zhou Hexuan can only sigh with emotion, the Chinese people these days are really difficult, even applying for a patent is so strenuous.

First of all, you must have money to buy a house in the UK, or start a company and set up a factory. Second, you have to convince authoritative institutions to approve, and these institutions are very bureaucratic, and they will not open their eyes if there is no benefit-even penicillin is turned away.

The United States is a little more convenient, but you must also have real estate. This is the express provision of the Paris Convention. People who are not members of the Paris Convention must have a fixed property in order to apply for a patent.

That is to say, for an overseas student with excellent grades, even if you have made a major research discovery, if you have no money to buy a house abroad, you can at most publish a few papers to gain reputation, and you are not even eligible to apply for a patent.

After Zhou Hexuan obtained the support of the University of London, the patent office was very efficient, and the patent right for sulfanilamide was approved within a few days.

Zhou Hexuan immediately ran to Albert with the patent certificate: "Your Highness, I have something nice for you to look at."

"Special...patent?" Albert was puzzled.

"Yes, a patent, a patent for a miracle drug," Zhou Hexuan explained, "This drug is called sulfonamide, which was discovered by a professor at the University of London, and I now own his patent rights."

Albert still didn't understand the situation: "Why did you let... let me see these?"

Zhou Hexuan said: "In current surgical operations, the postoperative infection rate is very high. Many patients have a high chance of dying of bacterial infection even if the operation is successful, and sulfonamide can effectively inhibit the growth of bacteria and greatly improve the survival rate of the operation. Medicines can save countless lives and even have the chance to win the Nobel Prize in Medicine."

"So... miraculous?" Albert was finally a little surprised.

Zhou Hexuan said with a smile: "I am going to invest in building a factory in London to manufacture this new drug. I hope His Royal Highness can take a stake."

"Why are you looking for me?" Albert was still confused.

Zhou Hexuan said frankly: "I am Chinese, and I may be troubled by setting up a factory in the UK. With the investment of His Royal Highness, it will definitely be unimpeded."

Albert smiled and said, "Don't worry, Britain is...a country that abides by business rules, and will not make...make things difficult for you."

Zhou Hexuan said: "Please be sure to buy shares."

Albert didn't care about it: "Okay, I'll invest... £1,000."

"Then I'll give you 10% of the shares," Zhou Hexuan said with a wink, "Your Highness, this is a super bargain deal."

"Perhaps," said Albert, not caring about the money.

Zhou Hexuan soon found Vivien Leigh's father. As a former successful businessman, Ornis quickly realized the great value of it. He promised to dispose of the factory in his hands as soon as possible, invest 8,000 pounds in exchange for 15% of the shares of the pharmaceutical factory, and be responsible for the operation and management of the factory.

Throwing away 25% of the shares all at once, Zhou Hexuan didn't feel heartache.

As a partner, if you don't give more benefits, why should you ask others to do their best?

British society is quite conservative at this time, countless times more conservative than the United States and France. It is difficult to do business in the UK as a Chinese. Prince Albert is like an umbrella, and Ornish is like a spokesperson.

As for why the pharmaceutical factory should be built in the UK?

Zhou Hexuan was also very helpless.

If you think about the fate of the founder of Yunnan Baiyao, you will know how terrible it is to build a sulfa drug factory in China. Sooner or later, it will be swallowed up by those in power, and China's chemical industry cannot support the production of sulfa.