Science and Technology Library

In the Capital Biogene Research Institute, Wang Yiyi, in his own experimental office, looked at the news about the Ridman virus and expressed his thoughts from time to time.

This human disaster has been maintained for several months, and the hardest hit areas have become so unimaginable.

Unfortunately, his research is to establish and optimize gene editing techniques in hematopoietic stem cells and T cells, to study the characteristics of related gene editing techniques, and to improve the efficiency and specificity of genes, mainly in the field of genetic diseases.

This time, the Ridman virus belongs to virology, which is not so serious in China. They do not need to participate in proximity.

The virus has caused panic in the international community, but he can do nothing.

After reading the news, Wang Yiyi put down the newspaper and sighed. Worried that other things are useless, it is the topic to do your own research.

Hey! !

Wang Yiyi was just preparing to start researching his own subject. An old man with glasses knocked on the door and walked quickly to him to see what was urgent.

"Director Liu, is there something urgent?"

"Dr. Wang, the dean came to inform that there was a breakthrough in the Deerman virus vaccine in Tangshan. Now it is carrying out urgent technical research and now needs experts in genomics."

Upon hearing this notice, Wang Haoyi stood up: "I am."

Waiting for Director Liu to speak again, Wang Yiyi has begun to pack up and prepare to leave the office.

......

East China Sea Life Science Research Institute.

Yang Yunjia quickly entered the lab, in the lab, with members of their team, as well as students and assistants.

Their team, the key research and development programs are precision medical research projects, epigenomics detection technology and clinical applications, as well as new techniques for RNA methylation epigenetic transcriptomics sequencing, both of which he conducted research.

The hot Redman virus outside is an immunology, but he is not an expert in immunology and virology, so he was not summoned by the medical team, and he continued to conduct research on the research side of the institute.

But today, the capital has come to inform that there is progress in the Reedman virus vaccine over the Tangshan Mountains, and experts from genomics experts are needed to participate in emergency technical research.

"Mr. Yang, what happened?" Standing in the lab, other members and students looked at him, and a student asked.

"The capital needs genetic editing and genomics to carry out emergency technical research, Yu Jun, Mi Shuangli, both of you and me."

“Mr. Yang, is it convenient to say what technology?” asked the female researcher named Mi Shuangli.

"The capital of Tangshan Hospital, analyze the genes of the Ridman virus vaccine."

"it is good."

The two focused on the head and did not hesitate to agree.

The CDC issued a notice of convening. The experts who are conducting genomics and bioinformatics research projects in various parts of the country received the news and did not hesitate to go to the capital Tangshan Hospital to carry out the project.

In just one day, nearly 20 genomics experts and researchers have arrived in Tangshan.

The staff of the CDC and the Ministry of Health are aware of the importance of the project, coordinate in the middle, quickly mobilize experimental equipment and materials, and prepare experimental conditions for researchers.

Tangshan Institute.

Chen Mo and Wu Bing, as well as team members, entered the conference room.

Several group members were surprised when they saw a room full of people. Some of them have been recognized, including the medical team's existing experts in genetic immunology, there are a total of thirty-three on the field, almost including the top experts in the field of genomics experts, including their former mentor.

It can be said that the most talkative people in domestic genomics are in this conference room.

They are looking at everyone, and the experts below are looking at them. Seeing the leadership of Chen Mo and Wu Bing, as well as the team behind the young, many people could not help but marvel.

It is this young team that has made great achievements in two bio-terrorisms, and this time it has made breakthrough progress when they are not optimistic. Seeing the group members, there are their own students, some academicians smiled with satisfaction, at least their students have a good time, they are also very proud.

However, with the lead Chen Mobi, it seems that genius has become dull, everyone's eyes quickly fell on Chen Mo.

In the past, I only heard the name, I didn’t see anyone, and I finally saw it today.

Chen Mo is also an expert and researcher on the field.

Their group can also find toxic proteins themselves, but in order to speed up, more people, obviously faster. The CDC and the Ministry of Health coordinated centrally, and the two hospitals supported it. It was unexpected to find so many researchers.

All the information was distributed, and Chen Mocai went to the podium of the conference room and went directly to the theme.

"This morning, we conducted another blood test on the patient. In your hand, there is an examination result. The patient has recovered the initial consciousness, and the antibody concentration in the body has increased compared with two days ago, and the number of viruses is decreasing. In theory, in about five days, the patient will develop resistance to the Ridman virus."

After Chen Mo opened, everyone listened carefully to Chen Mo’s explanation. Many people on the field were enough to be teachers of Chen Mo’s teacher, but Chen Mo’s level of performance was enough to be their teacher. The Ridman virus vaccine was a breakthrough under the auspices of his hands. No one dared to despise Chen Mo’s age.

When the vaccine was effective, many people were still a little happy, but just after some surprises, Chen Mo was interrupted.

"But we detected two venom proteins in the patient's body. These two toxic proteins also increased as the concentration of the antibody increased. Just two hours ago, the patient died in pain, less than five days later. He was not killed by the Riederman virus, but the poisonous protein in his body caused him to die.

We initially determined that this toxic protein is caused by the potential toxic protein gene in the mRNA of the vaccine platform system. So next, the task of all of you is to find the two virulence protein genes in the vaccine. We will find ways to knock out these two genes and eliminate the toxicity of the vaccine. ”

"Chen Chen, there are no two drugs that degrade the drug to achieve the purpose of treatment."

Hearing the following question, Chen Mo nodded and replied: "We have thought about this method. The medical team is looking for drugs that degrade the protein, but it has not been found yet, and it is not a cure."

"Academician Chen, a sample of toxic protein?" Yang Yunjia, sitting in the first row, asked questions.

"Yes, we have some samples in the patient's blood, but not many. After the project starts, samples of toxic proteins will be distributed to the laboratories. Next I will explain the related properties of the toxic protein and mRNA. Related information. If you have any questions, you can interrupt me during the period, or ask the academician Wu, we will try our best to answer your questions if the conditions permit."

After the explanation, Chen Mo began to talk about some of the characteristics of toxic proteins, as well as information related to mRNA, so that they can start research.