Rebirth of the God-level Xueba

All the expectations and fears of human beings about cloning are actually the knowledge of the future.

Clones from the 80s, or clones from 2010, have little practical application or need to be feared.

But if you use this as a starting point, by 2050, cloning will be as useful as it is terrifying.

On a technical level, this is mainly because cloning can be done very modularly.

The development process of cloning is very cumbersome, but if all the tediousness is locked into the module, it will be very simple.

Take the cloned sheep as an example. First, the cells of Sheep No. 1 are pulled out, and the nucleus is taken. This is the first module. The nucleus of Sheep No. 1 is stuffed into the enucleated egg of Sheep No. 2, which is the second module. The egg cells are stuffed into the body of Sheep No. 3, and Sheep No. 3 gives birth to a lamb. This is the third module.

The three steps, to simplify it, can be called taking the core, plugging the core, and laying the cubs.

If the three modules are broken, all of them can be automated, just like the PCR machine after 2010. You just need to find a cave with electricity, or any bad boy’s bedroom, and you can start to operate. cloned.

Imagine how comfortable it would be to use such a convenient technology in agriculture, medicine and animal husbandry. Even Chinese medicine will benefit endlessly. If you want to grind rhino horns, no problem, clone a rhino for you, or simply clone It is not difficult to get a rhino horn out - the new outlet will be the pharmacy scene, allowing customers to watch you clone a rhino on the spot, and you can ride it for a while before cutting the horn. The user experience is cruel and interesting.

If convenience is used to infringe on the rights of others, it may also be able to infringe on flowers. Not to mention high-end crimes such as terrorist organizations, when anyone with a complete set of equipment can clone a Wagyu, the Japanese will probably not be too happy. In fact, when the cloning technology was confirmed, Merino wool was required to be inactivated for export, but wool can be inactivated, and the inactivation plan for beef is somewhat difficult.

However, handy technologies are developed.

Standing on the land of China in 1988, Yang Rui first faced many difficulties.

The first step in cloning sheep is superovulation.

Yes, it is the same technology as the superovulation required for embryo transfer in cattle.

The reason why Yang Rui agreed with Ding Shiyi and others' plan to set up a genetic engineering laboratory in Haidian District was because many techniques of bovine embryo transfer can be used in cloning.

However, if you want to transplant directly without using your brain at all, you can't do it.

Not to mention one is superovulation of cattle and the other is superovulation of sheep. Even if it is the same cattle, different breeds have different requirements.

For Yang Rui's genetic engineering laboratory, which has not yet built a test site, the task is even more complicated. Because what they are facing is not the problem of transferring technology from cattle to sheep, but transferring technology from cattle to 34 kinds of sheep.

Yang Rui is not sure which breed of sheep will eventually be used to replace Dolly, so in the laboratory, he can only post a large blank paper, write the names of all 34 sheep on it, and try in groups.

Using hormones, not using hormones, in neutral environments, in light acidic environments, in light alkaline environments...

If all the possibilities were permuted and combined, it would not be enough to expand Yang Rui's genetic engineering laboratory by ten times.

Therefore, Yang Rui is just drawing a line. Once a sheep can test a suitable combination, it will be considered as a pass. If it cannot pass in the end, it will be considered as eliminated in the first round.

Some people may say, what is the relationship between superovulation and sheep cloning?

In fact, it is still the relationship between cost and time.

Because in the second step, putting the nucleus of sheep one into the unfertilized egg cell of sheep two, there will be countless failures.

The nucleus of Yangyi can be selected from various somatic cells, and the raw materials are unlimited.

The number of egg cells is limited.

If superovulation is not used, then more sheep are needed.

Thousands are not necessarily enough.

Why is South Korea's national scientist Hwang Woo-suk notorious? When he was doing cloning, because the egg cells donated by the society were not enough, he forced the female researchers and female students in the laboratory to provide egg cells. It was a terrible mess, and he basically stepped on the territory of evil scientists.

Although cloning sheep does not involve such problems, the egg cells that a sheep can provide are very limited. Therefore, sheep of breeds with low superovulation efficiency are basically unusable.

It is not without reason that it takes several years to clone a sheep.

Even though Yang Rui had already made many arrangements and preparations, it took almost three months to complete the establishment of Yang Rui's genetic engineering laboratory just in the first step of the second module.

And during this time, the first step of the first module, the removal of the cell nucleus, is still far away!

The 8811 project, which was just established, is so silent, which is really disappointing, so that the establishment of Yang Rui's genetic engineering laboratory has almost no signs of making a big deal. The scale ratio at the time of the Bell Awards is far from enough.

As the official representative, Hu Chi was very worried about Yang Rui's wild thinking. When he saw Yang Rui, he said, "Everyone knows that scientific research takes time. No one expects you to achieve results in two or three months. The media are all chasing you." It’s hot, it’s actually not easy to hear so many people coming this time.”

"That's right, Peking University, Tsinghua University and the Academy of Sciences have come forward together. Those who play in the science and technology sector must give face." Yang Rui teased, showing nothing on the surface.

Hu Chi became even more worried, and said: "It's not about everyone's face, it's about their confidence in you. Don't worry, as far as I know, the leader still trusts you very much. You just need to do research seriously. Besides, your The laboratory has just been completed, and it is just the beginning stage in terms of time."

Among the leaders that Hu Chi knew, he naturally included Mr. Qiao, and even referred to Mr. Qiao specifically.

Yang Rui immediately responded: "Thank you for the leadership's concern, but we have already started, and there will be no big problems in terms of progress."

"Don't chase the progress, it will affect your rhythm." Hu Chi is very considerate of Yang Rui.

He has experience in contacting the scientific community. He knows that many steps in scientific research can actually be changed. However, the fastest step is not necessarily the best way, and the model of achieving results in the early stage may not necessarily be beneficial to the later stage. Research.

For Yang Rui now, it is unnecessary to do research quickly and produce many small results, except for a little advantage in publicity.

What is the value of domestic media reports? If it is really necessary, all the media on the propaganda front must have the same caliber. Hu Chi is very worried that Yang Rui will not see this and choose the wrong way of expression.

Of course, Hu Chi would never remind scientists with ordinary relationships like this.

Yang Rui couldn't help laughing, and said, "I do it at my own pace, don't worry, I have no reason to catch up with the progress."

"I'm afraid you pay too much attention to the media." Hu Chi's worry cannot be said to be groundless. The power of the media is very powerful. A series of praises can easily make people feel elated, and a small amount of scolding can also make people depressed.

Yang Rui grew up among flowers, and he may be unhappy if there is less applause, not to mention that he has no results recently and is easy to be scolded.

A large amount of funds and policies have been invested, but after three months, there is only news of the completion of a new laboratory. Hu Chi can already imagine the seriousness of the media's righteous words.

Yang Rui smiled, and said: "If the media pays attention to it or not, if it can't affect the funding, it's nothing."

He blinked as he spoke, which made Hu Chi startled.

This is completely different from the scientists he is familiar with.

It can only be said that this is a deviation in the understanding of the two eras.

Scholars in the 21st century always pay the most attention to funding, followed by experimental conditions. With these two items, those who can make achievements are omnipotent, and those who cannot make achievements can also get some benefits.

But in the 1980s, scholars had a very different focus. Because scholars cannot move freely, they talk about politics in addition to science, and even the judgment of honor is not necessarily based on results. This makes everyone pay great attention to public opinion, not only the opinions of leaders, but also the voices of the masses.

In the 21st century, there are not so many troubles. Scholars who have made achievements can not only change jobs, but even go abroad. Therefore, although everyone cares about the opinions of leaders, they have no sense of fear of the masses, and social media is not the top priority.

When Yang Rui was a graduate student, funding has become the lifeline of scholars, and only with funding can he be qualified to talk about other things. Of course, liberal arts scholars still mainly talk about politics, after all, what they do are all subjective questions.

Under the watchful eyes of less than usual, but still large number of media, Yang Rui completed the steps of cutting the ribbon and speaking, announcing that the 8811 project has officially entered the experimental stage.

For Bo Gengxin and others, this also means that the confidentiality requirements have been raised by two levels.

"Any living thing in the yard, even a sheep, must be clean." Bo Gengxin looked solemn at the closed-door meeting of the confidentiality department.