My Life Simulator

A book list sent the gentle girl away.

Seeing Wen Wan's slightly trembling shoulders, Lu Li smiled and nodded. Although the basics are a bit poor, the learning attitude is still very correct! After getting my book list, look at her excited!

This is similar to... the excitement of elementary school students after receiving a box of practice questions, right?

Hungry for my body? You are thinking of peaches!

How can I have that American time to have a love affair with you? Might as well go back and do an experiment...

Well, Professor He kicked me out of the lab.

Then give the chicken a holiday... ugh, give yourself a holiday!

Lu Li turned around and walked out of the research institute, ready to go out for a walk and move his hands and feet.

Just as he walked to the gate of Fudan school, Lu Li suddenly saw a very familiar figure.

In the spring of March, catkins fly.

The light wind blows the weeping willows along the road, like rippling silk sash.

A woman wearing a light-colored spring dress, strolling in the shade of the tree, came in a light lotus step.

"Liu Qin?"

Lu Li was shocked. In this plot, he could still meet Liu Qin? It was... so unexpected.

"Land from?"

Hearing the call, Liu Qin raised his head quickly and saw Lu Li standing at the intersection in front of him.

The tall and straight figure, the handsome face, and the undisguised surprise on his face made Liu Qin's heart tremble inexplicably.

Reaching out his hand and brushing the hair by his ear, he calmed down, and Liu Qin walked up with a smile.

"Scientist Lu, old classmates are coming to visit, are you welcome?"

Walking in front of Lu Li, Liu Qin raised his hand and said hello with a smile.

"Dream!"

When facing Liu Qin, Lu Li was not steely at all, on the contrary, he was very active.

Hearing this, Liu Qin's face flushed slightly, pretending he didn't understand the meaning, and quickly changed the subject, "I only found out after reading the news, it turns out... I haven't seen you for a few years, you are already a world-renowned scientist. ."

"It's just a small achievement."

Lu Li said modestly, and then said to Liu Qin, "How about you? Have you graduated from Harvard?"

Does he know that I went to Harvard for a Ph.D.?

That means...he's been paying attention to me?

Liu Qin felt an inexplicable sweetness in his heart, and said to Lu Li, "I've already got my doctorate, and I'm just looking for a job!"

"Looking for a job? With your ability, a lot of units are rushing for it!"

Lu Li touted it slightly, and then said, "If there are too many units and you don't know how to choose... Why don't you come to Fudan and become a professor!"

"Come to Fudan to be a professor?"

Liu Qin glanced at Lu Li and said, "Does Fudan have any advantages?"

"The advantage is..."

Lu Li pointed at himself, "You can be closer to my handsome scientist."

"Cut~! Smelly!"

Liu Qin rolled his eyes at Lu Li.

The two talked and laughed all the way, and wandered around the Fudan campus.

Then... the gentle girl who was sent a list of books by Lu Li happened to see this scene.

damn it! what's going on?

Seeing Lu Li and Liu Qin talking and laughing all the way, Wen Wan's mouth was shaking with anger.

You are so steely in front of me, and you are so humorous in front of her?

You will send me the book list with me, and you will make her happy with her?

I...I can't compare to her at all...

Well, not really.

Although she is reluctant to admit it in her heart, but... in comparison, her appearance is not as perfect as Liu Qin, and her proud stalwart mind seems to be one size smaller than Liu Qin.

But...I won't admit defeat! Grab a man with strength, who is afraid of who?

Wen Wan took a deep breath, a smile appeared on her face, and greeted Lu Li and Liu Qin and walked up.

"Land from."

Wen Wan greeted Lu Li with a smile on her face, and then walked naturally to Lu Li, who was very close.

"This is……"

Wen Wan glanced at Liu Qin next to her, pretended to be a hostess, and said with a smile, "Is this a guest?"

Liu Qin's eyes shrank slightly, and an indescribable complexity surged in his heart. Such a hostess-like tone... Could she be Lu Li's girlfriend?

Lu Li also heard the gentle kiss from the hostess.

Is this intentional? Are you here to tear down my desk on purpose? If so, don't blame me.

So, Lu Li raised his head and glanced at Wen Wan, his face full of doubts, "That... Who are you? Do we know each other?"

Hearing this, a strange light flashed in Liu Qin's eyes.

But Wen Wan grinned in anger.

I only met half an hour ago, and you sent me a long list of books, so I pretended not to know each other?

Asshole!

Dare to do this to me? See how I clean up you!

So, Wen Wan pinched her thigh fiercely, and the pain made her tears flow down.

Then... Wen Wan looked at Lu Li with a sad face, without saying a word, with a heartbroken and weak look.

I go! Dramatic!

Luckily I'm not a vegetarian either!

Lu Li raised his eyes to look at Wen Wan, and said with a smile, "This girl, you pinched your thighs too much, and the flaws are too obvious."

"If you want to pretend to cry in the future, you can use ginger juice or balsamic oil. Rub a little on your fingertips and wipe your eyes, and the tears will come out, which will be more concealed."

"Pfft!"

Liu Qin next to him couldn't help laughing.

"Bastard! Can you spot this? Do you have microscopes in your eyes?"

Wen Wan bared her teeth for a while, stomped her feet fiercely, turned around and left. Pretending to cry was seen through, and I can no longer play.

"Sharp observation, this is an essential quality for scientific researchers!"

Lu Li waved at Wen Wan, "Student Wen Wan, remember to read carefully when you go back. Be sure to read the book list I gave you before. Next time, I will check your homework!"

"Damn book list!"

With a gentle roar, the footsteps of escaping became even more staggered!

After Wen Wan ran away, Liu Qin asked Lu Li, "Is she your student?"

"no!"

Lu Li smiled and replied, "A graduate student from Union Medical College came here to ask me for advice this morning. I saw that her foundation was not very solid, so I gave her a book list."

consult? Asking is just an excuse!

You even gave her a book list? How much steel are you?

But... when you were talking to me just now, why weren't you so steely? He has been constantly expressing hints, it seems that emotional intelligence is quite high!

Is it because of me...

Liu Qin's face was slightly red, but his heart was very happy.

In the next few days, Lu Li and Professor He took a leave of absence and took Liu Qin to play around in Shanghai.

Disney, golf, museums, the laughter and laughter of the two were left everywhere.

The life simulator is really amazing, the same girlfriend can fall in love countless times!

A few days later, Liu Qin was going back.

"Lu Li, I'm going back. After a few days of playing, my family urged me to go back."

"Then...I'll take it to you!"

Afterwards, Lu left the car and took Liu Qin to the airport.

Before getting on the plane, Lu Li carried a bag of fruit, handed it to Liu Qin, and said the famous words: pears are Li, and Lu Li's Li.

...

"Xiao Lu, sent your girlfriend away?"

When Lu Li returned to the laboratory, Professor He's face was full of "aunt smile".

"Well, send it back!"

Lu Li nodded, "She is thinking about coming to Fudan to apply for an economics professorship. She needs to discuss it with her family."

"Oh? Applying for an economics professor?"

Professor He was a little surprised. Could it be that Lu Li's girlfriend is also a scholar?

"She has a Ph.D. in economics from Harvard, and it should be no problem to apply for an economics professor."

Lu Li replied casually and didn't say more, "Professor, I'm going to do an experiment."

Harvard economics PhD? Dr. Returnee?

When Lu Li just made his world-renowned achievements, there was a returnee doctor with a background in studying abroad?

Out of prudence and protection of Lu Li, Professor He quickly reflected the situation and conducted a political review of Liu Qin.

...

Lu Xin was also very happy when he met Liu Qin again.

I fell in love again with my girlfriend in real life. This feeling... is really amazing.

It's just...it's still just a dream.

In this plot, falling in love is only incidental, and Lu Li's goal is still very clear. He must find a cure for cancer.

In the next time, Lu Li spent more energy and time in the laboratory besides calling Liu Qin and sending messages.

During the day, I do gene comparison experiments in the institute, and at night, I continue to conduct gene comparison experiments through the virtual laboratory.

But...the progress of this experiment is really frustrating.

The DNA chain has three billion base pairs, and it is too much work to compare them one by one to confirm the genetic information.

Even if the genetic information of 10,000 base pairs can be determined every day, it will take 300,000 days.

There are three hundred and sixty-five days in a year, and only 36,500 days in a hundred years. 300,000 days...

Lu Li only slightly compared the data, and felt a deep sense of powerlessness.

What's more, Lu Li couldn't complete the confirmation of 10,000 base pairs of genetic information in his daily experiments.

It can't go on like this!

Is there any other faster way?

Have!

At present, countries around the world are working on a new "gene expression" detection tool called "gene chip".

The sequencing principle of the gene chip is the hybridization sequencing method, that is, the nucleic acid sequence determination method is performed by hybridizing with a group of nucleic acid probes of known sequence, and the probes of the target nucleotides of known sequence are immobilized on the surface of a substrate.

When the fluorescently labeled nucleic acid sequence TATGCAATCTAG in the solution is complementary to the nucleic acid probe at the corresponding position on the gene chip, a set of probe sequences with completely complementary sequences can be obtained by determining the position of the probe with the strongest fluorescence intensity. Accordingly, the sequence of the target nucleic acid can be recombined. (Baidu came out, don't ask me, I don't understand)

A gene chip has countless gene probes integrated into the microgel, and the speed of "gene expression detection" can be increased countless times.

However, the current gene chip technology is only theoretical research, and the gene chip with real practical value has not yet come out.

But...the theory is enough!

"Virtual gene chip!"

With an order, a ray of light flashed, and a huge glass plate appeared in the laboratory. On this glass plate, numerous gene probe arrays are densely integrated.

This is a gene chip.

As long as there is a theoretical basis, the virtual laboratory can virtualize the finished product.

On the basis of the gene chip, with optical cables, consoles, computers, electron microscopes, monitors and other equipment, it can be virtually combined into a test bench.

After a while, various components were automatically matched to form a huge genetic testing test bed.

Then, Lu Li can perform gene expression tests.

Humans have currently confirmed that there are 100,000 genes with gene expression information, but... under the base number of 3 billion, 100,000 is completely negligible.

Another advantage of the virtual laboratory is that, as long as you think about it, you can come up with any kind of experimental materials.

So... Lu Li virtualized three billion cells that were missing a certain base pair.

Install these cells in the solution tank, start the genetic detection test bench, and let these cells with missing base pairs flow into the gene chip continuously, and the cycle and comparison are continuous.

On the display, various data surged like a waterfall, and gene expression testing was being carried out continuously.

The solution in the solution tank continuously flows through the gene chip, and is continuously recycled, circulating and running, never stopping.

It's so much easier!

Just wait for the test to complete and get the final result.

Lu Li let out a long sigh, put aside the unimaginably large amount of repetitive work in genetic testing, and began to study more interesting gene targeting technologies.

At present, in gene editing technology, how to accurately locate and how to make the spliced ​​protein cut to the desired position is still a matter of luck.

If all the genes in the human DNA chain can be deciphered and the gene expression information of each base pair can be confirmed, then... it is very important to accurately cut the required gene segment.

If you can hit the right spot at one time, you can hit all the shots without missing the target, it will undoubtedly increase the efficiency of gene editing technology thousands of times.

Existing gene editing technology relies entirely on transcriptase for gene positioning.

Transcriptase is like a radar. After transcribing the target gene, the transcriptase obtains the target information features, and then scans and searches the gene chain to align the target.

After finding the target, the transcriptase combined with the splicing protein will drive the splicing protein to fit the gene chain and cut the target gene.

In theory, this principle is completely correct. It's just that the "radar" is relatively ineffective, often finding the target, or even finding the wrong target.

Now, what Lu Li has to do is how to improve the radar's search capability.

But... it's hard to do!

Transcriptase is a very simple protein molecule, and there is absolutely no possibility of replacement on the "hardware device".

The hardware can't do anything, and the only way is to update the software to improve the resolution.

To improve the discrimination ability of transcriptase, it is necessary to master all the genetic information on the gene chain.

Well, back to square one.

Or we can only do gene expression testing first, and first determine the gene expression information of three billion base pairs.

Engaging in genetic research depends entirely on how much human beings know about genes!

A long way to go!