I Can See Health

  Chapter 592 The Magazine's Reply

   One area in the heart, the doctor's office.

   Everyone was stunned when they heard Lu Chen's words, then shook their heads.

   "Impossible, the patient has chest pains!"

   "I have never seen a patient without disease with this kind of electrocardiogram..."

   "Lu Chen, at least you have to rule out other diseases before you can finally consider the physiological situation?"

  …

   There was a lot of discussion, and they were not very supportive of Lu Chen's "no disease theory".

  In medicine, there is a default rule that considers the physiological abnormalities of patients, after excluding all possible diseases.

   For example, in a patient with proteinuria, you may need to exclude kidney disease before you may consider physiological proteinuria. (Physiological proteinuria can be seen in changes in body position, strenuous exercise, high temperature, etc.)

  It is impossible to consider that proteinuria is caused by physiological conditions from the beginning.

   Su Rui on the side also looked at Brother Lu Chen curiously.

  She has been with Lu Chen for a while, and she knows her brother's character, and she is definitely not the kind of person who is aimless.

  Lu Chen must have his own reasons for saying this.

   She quietly looked at Lu Chen, looking forward to his next words.

   After Lu Chen and others finished expressing their opinions, he cleared his throat and said, "Teachers, have you seen the electrocardiogram of black people before?"

   As soon as these words came out, everyone was a little confused and shook their heads.

  Although Kyoto is an international metropolis, foreigners who come to the First Affiliated Hospital of Kyoto for treatment will always go to the International Department, and rarely come to them.

   And African medicine lags behind, and it is rare to see black doctors appearing at global conferences.

  Xiao Shikang was also in the office, he asked aloud: "Lu Chen, you mean different races have different electrocardiogram performances?"

  Lu Chen nodded, "Yes, in fact, this is well understood. For example, the recommended dosages in many clinical guidelines are different for different races, such as warfarin, rosuvastatin and other drugs..."

  Warfarin, an anticoagulant drug, at the same dose, yellow people are more prone to bleeding complications than white people.

  Xiao Shikang frowned, "It's just a drug, it doesn't represent changes in the electrocardiogram. As long as the black man's heart is on the left and its position in the chest remains the same, the electrocardiogram graph shouldn't change."

The principle of    body surface electrocardiogram is to use an electrocardiograph to record from the body surface the pattern of changes in electrical activity generated by the heart during each cardiac cycle.

   When everyone heard Xiao Shikang's words, they nodded in agreement.

  Lu Chen shook his head. When it comes to electrocardiogram and electrophysiology, that is his strength!

   "Mr. Xiao, you may have overlooked one point, and that is the adaptation of the heart."

  Xiao Shikang frowned deeply, "Adaptive change?"

  Lu Chen nodded slightly and continued: "Race is one of the main factors that cause adaptive heart changes in exercise. More than two-thirds of black athletes have repolarization changes in the electrocardiogram."

"Including J-point elevation and ST-segment arched dorsal elevation in the precordial leads (V1-V4), as well as T wave inversion, in the absence of other clinical or ECG features of cardiomyopathy, the above ECGs appear to be normal variants, No further screening is required."

   The black man on Lu Chen's hospital bed was an athlete by profession.

  In the Cardiology Office, it was difficult for everyone to digest Lu Chen's remarks for a while.

   "Lu Chen, you mean, this patient doesn't need any other tests?" Xiao Shikang asked tentatively.

  Lu Chen nodded slightly, "No need, he should be a normal physiological change."

   "Then how to explain his chest pain?"

  Lu Chen thought about it and said, "I have carefully asked the patient that he was exercising vigorously when the chest pain occurred, so I think that his chest pain is most likely caused by excessive exercise."

   "This..." Xiao Shikang was stunned for a moment, but didn't say much.

   All of the young generation leaders in the field of cardiology will definitely not easily listen to Lu Chen's words.

   One of the resident physicians who had just arrived in the department said, "Lu Chen, is there any literature to support what you said?"

  Lu Chen nodded without hesitation: "Of course, it was mentioned in the latest issue of the electrocardiogram analysis of international athletes. If you are interested, I can send the literature to the group."

   This document was also found by Lu Chen just now.

   There is a "Literature Reading" skill card. It is very easy to find this kind of document.

   "Lu Chen, send it to the group!" the resident doctor said quickly.

   "Okay." Lu Chen smiled and nodded.

   Everyone is very interested in this new knowledge.

   Especially this theory is completely contrary to everyone's normal thinking mode!

  The profession of medicine is to keep learning and rely only on experience to treat diseases, and sooner or later it will be eliminated.

   Everyone clicked on the literature that Lu Chen posted in the group.

   Not long after, Lu Chen noticed the prompt popped up from the system panel.

   "Congratulations, +1 for receiving thanks from Xiao Shikang!"

   "Congratulations, +1 for the thank you from Su Rui!"

  “…”

   Looking at the series of thank you points, Lu Chen sighed in his heart, and he successfully put on another wave.

   What makes Lu Chen the most delighted is that the completion of the system upgrade has also improved, and the next upgrade is one step closer!

  …

   Find the correct diagnosis, the next diagnosis and treatment plan, that is, let the black people decide.

   "Doctor Lu, are you saying that my electrocardiogram performance is physiological?" The black man also showed a smile.

   Actually, he also felt that he had no major problem, but the doctor at the school hospital was too nervous.

"Well, we rarely see foreigners." Lu Chen explained patiently, "but we read the international clinical guidelines, and about two-thirds of black athletes have this kind of electrocardiogram performance, so it is a normal physiological phenomenon. , do not need to be dealt with for the time being.”

   "However, if you are worried, we can complete further cardiac examinations for you, such as cardiac ultrasound, cardiac angiography, etc."

   The black man shook his head quickly, "Doctor Lu, I trust your judgment. Well, I also have doctor friends in Africa. Let me tell them about the situation here."

   "Of course." Lu Chen nodded.

  International guide, just a piece of paper, if it can be verified in reality, it is the best.

   Then, the black people began to contact their doctor friends in Africa.

   for a long time.

   The black man came to the doctor's office and found Lu Chen.

   "Dr. Lu, you are really amazing!" The black man showed his white teeth, "My friend in Africa said that my situation is indeed common!"

   When everyone in the office heard the black man's words, they became more convinced of Lu Chen's previous remarks.

   I didn't thank Lu Chen just now, but this time, I finally gave Lu Chen a thank you.

  Lu Chen smiled slightly, this black man has a high emotional intelligence, he knew that he would come to the office to praise him.

   "In that case, you can leave the hospital."

   After all, the black man had an electrocardiogram and a blood test, but he still had to pay for it. Su Rui processed a 24-hour admission and discharge record, and the black man was discharged.

  …

   After dealing with this black patient, there was a brief silence in the doctor's office in the first district of the heart.

  Lu Chen was looking at the system panel, calculating how long it would take him to upgrade the system next time.

   At this time, the beautiful little sister Su Rui suddenly came up to Lu Chen.

   A faint scent was refreshing, which made Lu Chen's heart sway.

  Single solo for so many years, even Lu Chen, a veteran cadre, was very difficult to withstand this test.

   "Brother, this black man gave me an idea just now." Su Rui said softly.

   "You said it." Lu Chen kept his mind and didn't look sideways.

Su Rui thought for a while, and said slowly, "Senior brother, in the national nature project you are doing now, the experimental group is the yellow race, and AstraZeneca's experimental group is the white race. Actually, think about it, there is not much conflict, right? "

  Lu Chen looked at Su Rui in surprise, this little girl is not bad!

   can actually draw inferences from one case to another. From the black patients, I think of the national natural experiment project.

   It will definitely be a good seedling for scientific research in the future!

   "How do you say this..." Lu Chen touched his chin, Su Rui was right, but she ignored a very important point, "In your opinion, where is the most developed medicine in the world?"

   "Europe, America, Japan." Su Rui said, "Most of the clinical treatment guidelines are written by experts from European and American countries. Our Chinese medical experts are translating them and making minor changes to become domestic guidelines."

   "Well, that's a good point." Lu Chen nodded, "Then you say, under the same conditions, I study the yellow race, and AstraZeneca studies the white race, who has the most influence in the end?"

  Su Rui was stunned, "It should be AstraZeneca. However, this does not affect our research results, after all, the research objects are different."

"It does not affect our results. However, compared with AstraZeneca, if our research results are slower than theirs, the number of experiments is less than theirs, and the statistical methods are lower than theirs, then our Do the research results have any international influence?" Lu Chen asked slowly.

  Su Rui glanced at Lu Chen, "Everyone will say...that we are plagiarism and plagiarism?"

   "Yeah." Lu Chen nodded slightly, "Not only does it have little influence, it is very likely that others will call it AstraZeneca!"

  Although Lu Chen didn't want to think about it, this is the reality.

   China's medicine is indeed lagging behind the international level. Although it is catching up non-stop, and in some fields, it is already at the forefront of the world, but in general, there is still a big gap with the powerful countries such as Europe, America, and Japan.

  Why did Lu Chen work so hard to catch up with AstraZeneca?

  Because once he slacks off and asks AstraZeneca to complete the experiment ahead of schedule, then his experimental results will not be able to make a splash in the world at all, and he can only enjoy himself in China.

   "Senior brother, when did you say that China can surpass foreign countries?" Su Rui sighed slightly. Medical students place great importance on English ability, because most of the top literature is from Europe and the United States.

  Lu Chen was slightly startled when he heard Su Rui's words, surpassing Europe, America and Japan?

   A seed sprouted slowly in Lu Chen's heart.

  Lu Chen murmured in his heart: "Yes, there will be such a day!"

  …

   Across the ocean.

  USA, Harvard Medical School.

   Fan Boyan, as a reviewing editor (peer reviewer) of the journal BasicResearchincardiology, will be assigned to review one or two papers every once in a while.

  He came to the United States for many years, and after his own efforts, he was successfully appraised as an associate professor at Harvard Medical School.

  As a Chinese, this is also extremely rare in Harvard Medical School.

   Today, Fan Boyan received another email from the editorial department of "BasicResearchincardiology", "Professor Fan to help review the manuscript."

   Fan Boyan happened to be free, so he clicked on the email.

  As a peer reviewer of a paper, he has a lot of power to decide the final result of an article.

  There are generally three peer reviews for each paper. As long as it can be favored by two experts, it can basically be accepted by the editor-in-chief.

   Peer expert review is divided into single-blind and double-blind. "BasicResearchincardiology" chooses double-blind, that is, the contributor and the reviewer do not know each other's identity.

   "The habit of reading this English study is so authentic. It should also be a thesis of some European and American university or research institute."

  As a Chinese native Fan Boyan, he is very aware of the English writing habits of contributors from all over the world.

   In general, people from other countries, even if their English level is professional, the way of writing papers is close to the way of thinking in their own countries.

   The paper in front of him, the first glance Fan Boyan saw, was too authentic.

   It is absolutely impossible for it to come from the handwriting of people from other countries.

   "Hey, this is still about Dapagliflozin!" Fan Boyan murmured, "Could this be another AstraZeneca paper?"

  Recently, Dapagliflozin is a big hit in the international cardiovascular drug field!

   Fan Boyan has also read several papers on AstraZeneca's research on dapagliflozin.

   "I remember that in China, there seems to be a laboratory researching dapagliflozin, and it has also published several good papers."

   Fan Boyan will dabble in this cutting-edge hot field.

   In particular, this time, the research team of "Dapagliflozin" is also from China!

   This was a big surprise for Fan Boyan.

  As a Chinese person, although he is in the United States, his heart is in Huaxia. He is always concerned about the information in the domestic cardiovascular drug field of Huaxia.

  Fan Boyan threw away the distracting thoughts in his mind and continued to read.

   "Hey, something is wrong!"

  As a professor and doctoral supervisor in the cardiovascular field, he immediately noticed the abnormality of this paper.

   "The statistical method used in this paper is not right!"

   It’s not that the statistical method is too bad, on the contrary, it’s too good!

   For this type of clinical research experiment, such high-end statistical methods are simply not used.

   The same conclusion can be drawn with only a slightly lower level of statistical methods for sports.

   Fan Boyan frowned slightly. He paused reviewing the paper on "Dapagliflozin", but found the papers published by AstraZeneca.

   In this comparison, Fan Boyan discovered an anomaly.

   The papers published by AstraZeneca have never tried such advanced statistical methods at all.

   How can a "special case" suddenly appear?

   "Is this paper in my hand not published by AstraZeneca?"

   Fan Boyan was taken aback by this thought in his heart!

   If it is said that it was not published by AstraZeneca, then isn’t this published by the laboratory in China?

   "When did China dare to do this kind of scientific research competition with AstraZeneca?"

  Fan Boyan still couldn't believe it.

   In his subconscious mind, aren’t the domestic scientific researchers following behind countries such as Europe and the United States in translation work?

  If it is really a domestic laboratory... Thinking of this, Fan Boyan has a faint expectation in his heart.

  …

  …

  …

   The First Affiliated Hospital of Kyoto University.

   The doctor's office in the first district of the heart.

   "Lu Chen, you have been in Kyoto for about two months, haven't you?" Xiao Shikang asked Lu Chen.

   "Well, almost." Lu Chen nodded slightly.

   Time flies so fast, half a year of communication life has passed in a blink of an eye.

   "The postgraduate departments in the academy, the students who ask you to come to exchange, all submit a summary." Xiao Shikang said, "The main thing is to talk about what you have done in the past two months, what gains or achievements."

   "Okay." Although Lu Chen wasn't interested in this kind of thing, but what the hospital asked, he could only do it.

   Go back to the bedroom.

  Lu Chen started to prepare the monthly summary.

   He heard that the academy will also give certain rewards to outstanding students.

   The specific criteria for judging is still unknown.

   "It's been two months so soon!" Lu Chen muttered in his heart, not much time left for them to conduct clinical research experiments!

  According to the previous deployment, if he cannot publish a high-scoring SCI paper within two months, and cannot prove that he has the strength to compete with AstraZeneca, then he can only lie down!

   "Time is running out."

   At this time, Lu Chen could only look forward to the reply from "BasicResearchincardiology" magazine.

   As for the rest of the research team.

   Ke Yue's paper has been accepted, which is good news!

   As for Gu Xinyue and Wang Zihao, because of their lack of experience, the thesis they completed together was returned for revision.

   The other party did not directly reject the manuscript, but returned it for revision, which also means that there is still a chance.

  Lu Chen was relatively free for the time being. Taking advantage of this opportunity, he happened to help Gu Xinyue and Wang Zihao revise their papers.

  …

   In the blink of an eye, another week has passed.

  The paper that Lu Chen helped Gu Xinyue and Wang Zihao revise was also accepted by the magazine!

   For this, Wang Zihao was excited for several days, and even Lao Gu, who had always been aloof, had a long-lost smile on his face.

   However, neither Ke Yue's thesis nor the papers of Gu Xinyue and Wang Zihao are the decisive factors.

   They have 2 points and 3 points. Compared with AstraZeneca's paper, they really can't make it to the table, so they can only make up for it.

   "Lu Chen, hasn't your magazine replied yet?"

   Wang Zihao asked while the research team was having lunch together.

  Lu Chen shook his head helplessly: "Not yet."

   "If there is no reply this month, is our experiment..." Ke Yue whispered, her expression was a bit bitter, she also devoted a lot of effort to Lu Chen's national nature project.

   Hearing this, Lu Chen did not respond, and the atmosphere at the scene was a little dull.

  Everyone understands that if Lu Chen's paper has not been accepted within this month, then this national natural project can only be declared to be flat, and it will not be able to compete with AstraZeneca.

   "It's nothing, everyone be happy." Seeing that everyone was in a bad mood, Lu Chen could only comfort him, "We are still so young, even if this time is unsuccessful, there will be more opportunities in the future!"

   Having said that, everyone was still a little unwilling.

   Just when Lu Chen was about to continue comforting everyone, suddenly, his phone vibrated slightly.

   Thought it was the sound of WeChat, when he took out his mobile phone and looked at it, several large characters appeared on the notification bar: "You have a new email, please check it!"

  Lu Chen was startled, new email?

   Could it be...

   At this time, Wang Zihao came over to take a look, and he said in surprise, "New mail!"

   When everyone heard this, they all looked up at Lu Chen.

  Lu Chen swallowed softly, he had never been so nervous before...

  Unlock the phone and click on the information in the notification bar.

  The interface jumps, enters the mail APP, and then enters the inbox.

  Lu Chen stared at the sender's message, then paused slightly, looked up at Ke Yue and the others, "It's a reply from the magazine."

   Hearing Lu Chen's words, everyone sat upright and stared at Lu Chen, not daring to let out the air.

   After thinking about it, in the future, try to have as many words in each chapter as possible, so as not to separate, and think about the title, which is too troublesome.

   ps: As a front-line clinician, it is too difficult to keep changing!

   After all, it is impossible to update after two consecutive night shifts.

   However, I will schedule, work hard, and update as much as possible.

   (end of this chapter)