I Can See Health

Chapter 321 Research to change clinical guidelines?

"Lu Chen, there is a male patient who needs a urinary catheter. Please come and help. He is in bed 10."

Gong Nannan walked into the doctor's office and smiled at Lu Chen.

"Okay, coming soon."

Lu Chen was writing down the course of his illness. When he heard nurse Gong Nannan's words, he stood up and walked out of the office.

Since Lu Chen came to the emergency department, many male patients had to leave all matters of urinary catheterization to him.

Therefore, urinary catheterization became one of the skills for which Lu Chen's proficiency reached 100% the fastest.

Bed No. 10 is a young man in his twenties.

"Don't be nervous, you'll be fine soon." Lu Chen came to the bedside of bed No. 10.

The young man looked green and a little embarrassed, and whispered: "Oh, please be gentle."

"Don't worry, take off your pants first." Lu Chen placed the catheter bag on the bedside console.

"Ah? This..." The young man's face turned red.

"What are you afraid of? You're all a big man." Lu Chen said sternly, "It will be over soon."

"Oh." The young man took off his pants hesitantly.

About a minute later.

"Okay." Lu Chen smiled and said to the young man in front of him, "There's nothing uncomfortable."

The young man nodded: "Thank you."

Lu Chen wrapped the remaining medical waste and threw it into the yellow medical waste barrel.

"Congratulations, I received a +1 thank you from Ma Ping!"

A urinary catheter was inserted and I got some gratitude points.

Lu Chen left the emergency ward with satisfaction.

"Hey, Lu Chen, I heard that our opening time for this year has been advanced."

As soon as he returned to the doctor's office, Cheng Peng came over.

"When will it be advanced?" Lu Chen was stunned.

He has been busy doing clinical research data recently, and he really didn't notice these things.

The topic proposal involves the direction of the topic and determines the research direction for the entire three-year postgraduate program.

"Probably after New Year's Day." Cheng Peng thought for a while.

"After New Year's Day?" Lu Chen frowned.

The national electrocardiogram competition takes place almost during New Year's Day.

In other words, after he finishes the competition and returns to school, he will almost have to start the project.

"It's not because something happened to a certain star. He got a Ph.D., and even CNKI doesn't know what it is." Cheng Peng pouted, "Now the Ministry of Education has stricter review of papers. In the past, the duplication rate was no more than 20%. In our current class, the score is less than 10%, which is so weird! So in order to allow us to prepare the paper earlier, the school has moved up the time for opening the paper. "

Lu Chen also heard about this celebrity.

However, the quality of Huaxia's papers is indeed poor now. Many of them are just one article, or they can be graduated after translating foreign texts.

"Time is running out." Lu Chen thought to himself.

The usual question opening time is the start of the second semester, but this year it has been moved forward to the first semester.

Lu Chen has some ideas for his clinical topic, but he still needs preliminary data support.

He is currently doing research on this early data.

If even the early data is meaningless, then there is no need for him to continue.

The most important thing now is to get the early data out quickly before New Year's Day.

Eight zones in the heart.

Office of the Director.

Lu Chen, Ke Yue and Jiang Qingyan stood in front of the desk.

Li Yao looked down at the proposal reports of the three people.

Sometimes the corners of his mouth are raised, and sometimes his brows are wrinkled.

A long while.

Li Yao said slowly: "Well, Jiang Qingyan has a good idea. The research direction of the toxic effects of anti-tumor drugs on cardiovascular disease is very interesting. Research in this field abroad is very mature, but it is still in its infancy in China. "

"But, Ke Yue, your proposal report..." Li Yao raised her head and glanced at Ke Yue, "How should I put it, studying the relationship between platelet aggregation and cardiovascular disease doesn't seem to be a problem, but have you ever read it? Other people’s research documents?”

Ke Yue lowered her head, "Look, I've seen it..."

"Then you should also know that there are already many mature research and development results in your research field. If you try it again, although there are no fatal problems in the entire research topic, it will be difficult to make something more innovative. In a word, it is like tasteless , It’s tasteless to eat, it’s a pity to throw it away.”

"Yes." Ke Yue's voice was thin and weak, "Teacher, I will look for the literature when I go back."

Li Yao nodded and said nothing more.

Only Lu Chen's proposal report was left, and Li Yao did not express any opinions.

It was a little quiet in the office.

Li Yao tapped her right index finger on the table, making a small and regular sound.

After a long while, Li Yao raised her head and looked at Lu Chen.

"Regarding the study of dapagliflozin in preventing early heart failure in patients with acute myocardial infarction, was this research topic your own idea?"

Ke Yue and Jiang Qingyan looked at Lu Chen standing aside.

Is there any problem with this topic?

Lu Chen nodded slightly.

In fact, with the help of the system, he applied the clinical scientific research skill card and combined it with the current popular research field of cardiovascular medicine.

Finally, I finally came up with this research topic.

"Very good, very good!" Li Yao said twice in a row, "Dapagliflozin is a relatively hot drug currently. It is being studied by major laboratories around the world. And the research and development direction you have chosen is currently being studied both at home and abroad. It should be blank! If you can do it well, there will be no problem in publishing a high-scoring SCI.”

"Even if the sample size of the study is large, a large-sample, multi-center clinical study is conducted, and the final research and development conclusions can be obtained, which can even change clinical treatment guidelines!"

Change clinical guidelines?

Everyone present, including Lu Chen, looked shocked.

Lu Chen originally just wanted to publish an SCI paper, but he didn't expect Li Yao to give such a high evaluation.

Ke Yue and Jiang Qingyan looked at Lu Chen in disbelief.

No one would have thought that a proposal report produced by a graduate student might change clinical guidelines!

Li Yao continued: "Don't be so surprised, you need to know. Dapagliflozin has just been included in the conventional drugs for the treatment of heart failure. The medical field has recognized its status. However, in current clinical practice, it is not used in acute cases." Research on myocardial infarction, so it has not been included.”

"but……"

Li Yao changed the topic and stared at Lu Chen closely: "As we all know, clinical research is not so rare because of its methods! It requires a lot of manpower, material and financial resources! The sample size you wrote in your proposal report is only five Ten people, this kind of sample size, can only publish one low-scoring SCI paper. If you want to change clinical guidelines, the number of such studies will be at least tens of thousands! Generally, this kind of research to change clinical guidelines is based on leading hospitals in the country. Leading major tertiary hospitals, the sample size is large, so that such research results are suitable for clinical use. "

Lu Chen nodded, he understood what Li Yao meant.

In clinical scientific research, good ideas are important, but they also require a lot of financial and material resources.

In a prospective study, a sample of only fifty people is definitely not enough. It can even be said to be very, very few!

But with a sample size of fifty people, the amount of money needed to spend is tens of thousands, or even more.

This is also the limit that Lu Chen can bear at present.

Spending more money on clinical research is not realistic for Lu Chen now!

"Let's do this." Li Yao continued, "Lu Chen, you first make a sample size of fifty people. If the preliminary experimental research is meaningful, then we will consider whether there is any possibility of going further."

"Good teacher." Lu Chen smiled.

"Actually, the sample size of these fifty people costs a lot of money." Li Yao said solemnly, "I will give you a partial subsidy in the name of the laboratory. Secondly, when you collect data, I will let you know The medical care in the inner eight districts will cooperate with you.”

The so-called prospective research requires patients to return to the hospital for review in a timely manner, which involves examination fees, round-trip travel expenses, etc.

"Thank you, teacher!" Lu Chen looked delighted.

His biggest obstacle now is not actually funds, but that if he wants to conduct clinical experiments well, he must have the cooperation of the medical staff in the department, otherwise it will be difficult to collect first-hand data.

Now that Li Yao has this Sword of Shangfang, Lu Chen's future clinical research should be much easier.

"By the way, so are you two." Li Yao said to Ke Yue and Jiang Qingyan, "I will ask the nurses in the department to cooperate with you."

"Thank you, teacher." Ke Yue and Jiang Qingyan said in unison.

When they walked out of the director's office, Lu Chen and the three of them had happy looks on their faces.

As a mentor, Li Yao is already quite responsible for being able to do this.

Many graduate tutors basically leave students to fend for themselves.

Some tutors will even impose some unreliable research on their students.

Li Yao was very pleased to see the three people leaving the office.

The quality of students in this class is too high.

Lu Chen and Jiang Qingyan's clinical research topic is very innovative and should produce good results.

Ke Yu's subjects were worse, but he was qualified for graduation.

Li Yao did not provide such convenient conditions to the students of the previous two years.

This can be seen from Senior Sister Wang Shasha.

"I hope the three of them won't disappoint me."

Li Yao looked at the three proposal reports in front of her with a smile on her face.

After leaving the doctor's office, Lu Chen and the three of them walked along the path of the hospital.

"Lu Chen, you are so awesome. The teacher said that your topic can even change clinical guidelines!" Ke Yue couldn't help but give Lu Chen a thumbs up.

"That requires a large sample size. I only have fifty samples now, which is enough to publish an SCI article." Lu Chen smiled.

It's not that he's being modest, it's just the sample size.

"Oh, it's already great!" Ke Yue said with a smile.

At the same time, she felt happy.

It seems that helping Lu Chen record data is a very correct choice!

If Lu Chen published an SCI article with her name on it, he would make a lot of money.

"Jiang Qingyan's topic is not bad." Lu Chen smiled, "Ke Yue, you have to revise your proposal report."

Jiang Qingyan smiled.

Ke Yue pouted, "Hey, I know, it looks like I have to stay up late again..."

The three of them chatted all the way and separated in front of Guipei's dormitory.

Back in the dormitory, everyone in the dormitory was discussing the topic.

"The preliminary data of my project is almost done." Wang Zihao patted Lu Chen on the shoulder, "I still have to thank Lu Chen for this! Without you, I wouldn't be so fast."

"Hey, I don't even have any ideas, and I'm about to start the project. It's really difficult!"

Another roommate Xing Yu frowned.

"Brother Yu, go ask your boss! Doesn't he have any projects?" Wang Zihao asked in confusion, "Just let you do a sub-project, it should be enough for you to graduate, right?"

"Hey, I asked." Xing Yu smiled bitterly, "My boss asked me to think about it myself, and then let him change it after I think about it. As for his project, I don't think he can handle it himself. He is looking for an outsourced laboratory to do it. If you want him to give me a sub-project, forget it."

"Uh... It's really difficult for you to meet an unreliable boss." Wang Zihao shook his head slightly, and then looked at Lu Chen on the side, "Lu Chen, have you finished your clinical project?"

"The opening report has been written, but the preliminary data has not been completed yet." Lu Chen shook his head.

"Then hurry up." Wang Zihao said, "I remember you are going to Bingcheng to participate in the electrocardiogram competition, right? When you come back from Bingcheng, we will almost have to start the project."

"Yes." Lu Chen nodded, "I asked two classmates to help, and they should be able to complete the preliminary data."

"That's good." Wang Zihao said.

The dormitory chatted for a while.

Wang Zihao suddenly received a WeChat message. After reading it, he said, "Lu Chen, my sister wants to treat you to dinner again."

Lu Chen was processing clinical research data, and was stunned when he heard this.

"Didn't she eat it some time ago? Why eat it again?"

"Last time it was a thank-you banquet, and this time she is going to come to the hospital for a follow-up visit." Wang Zihao said, "So I want to make an appointment with you in advance to learn some information from you."

"This... is not necessary." Lu Chen said, "Your sister is coming for a follow-up visit, just let her go to the cardiology clinic. I can't prescribe medicine or do any tests here."

"I told her all this, but she still wants to come to you." Wang Zihao said, "Lu Chen, just think of it as a free meal, it's only a morning anyway. So that my sister won't bother me again."

Lu Chen thought for a while and said, "When?"

"Tomorrow is the weekend, UU Reading www.uukanshu.net just let him know, 11:30 noon, at the Shangri-La Hotel."

"Shangri-La... isn't cheap?" Lu Chen smiled.

"Don't worry, my sister is a rich woman." Wang Zihao smiled, "You can't make her poor even if you eat a few more meals."

At this time, Xing Yu whispered beside him: "Zihao, I also want to have a meal, I don't want to work hard..."

"Go away, go away." Wang Zihao laughed and scolded, then looked at Lu Chen, "What do you think, do you want to go?"

Lu Chen nodded: "Since you said so, I will definitely go. But can we change the place? The restaurant in front of our hospital, the taste is very good, the price is also affordable, I still have to process data tomorrow afternoon. Besides, going to a high-end Western restaurant like Shangri-La is too restrained, and the appetite is not much better."

"This should be no problem, I will contact my sister." Wang Zihao smiled.

...

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